dualguide - progress
goal: demonstrate the importance of barcoding by showing that relying solely on tumor burden results in loss of information volcano plots (fig1_volcano_plots.pdf) x-axis: log2(original value), y-axis: -log10(p value) 90th percentile, ln_mean, n_of_tumors, tumor burden results more negative effects with number of tumors possible correlation between 90th and lnMean and tumor burden note remember we discussed that the titer was not calculated as usual, if exact numbers are needed, i will verify them "4type plots" (fig2_4type_plots.pdf) two growth measurements, a pair (ie. Apc_Lkb1 and we calculate the effect from Apc and from Lkb1 as well, so more points on the plot) 4 types: not significant with either growth measurements significant with both growth measurements significant with only the first gm significant with only the second gm our plots: one growth measurement is always the tumor burden, so we have three plots: tb vs 90th, tb vs lnmean, tb vs number of tumors significant ...